As the new Viper, she kidnappedRoxxon president Hugh Jones, in order to put him in thrall of the Serpent Crown.

Madame Hydra helped Jordan Stryke, asupervillain codenamed Viper, escape custody in Virginia, only to proceed in assassinating him, and usurping his codename and leadership of the group known as the Serpent Squad. Some time later, it was revealed that the Space Phantomhad exchanged places with her, and her whereabouts at the time were undisclosed. However she was apparently killed when Captain America and Rick Jones dodged missiles she fired at them and she was caught in their explosion. She capturedRick Jones to bait a trap for Captain America, and then subdued theAvengers with gas, planning to bury them alive, and battled Captain America again. She eventually rose through the ranks of Hydra and frequently came into conflict with Captain America and the organization known as S.H.I.E.L.D. She first appeared as a leader of Hydra under the codename Madame Hydra, and first fought and captured Captain America while trying to contaminate New York City's water supply. For twenty-two years, Ophelia excelled and became Kraken's best student. Among twelve other girls, Ophelia was taken in by Hydra and raised by Kraken. Part of her face was scarred at one time, although it has since been healed. Ophelia Sarkissian was orphaned as a child in Central Europe (Hungary). Viper was created by Jim Steranko and first appeared in Captain America#110 (February 1969).

Madame hydra